Table 3.
Effects of S-23 on hormones and fertility
| Group | EB (μg/d) | S-23 (mg/d) | Animal numbers | LH (ng/ml) | FSH (ng/ml) | Number of pregnancies |
|---|---|---|---|---|---|---|
| 1 | 6 | 0.21 ± 0.050 | 5.6 ± 1.2 | 12/12 | ||
| 2 | 5 | 5 | < 0.04I | 5.2 ± 0.43 | 8/10 | |
| 3 | 5 | 0.05 | 6 | < 0.04I | 4.8 ± 1.4 | ND |
| 4 | 5 | 0.1 | 6 | < 0.04I | 4.8 ± 0.90 | 0/12 |
| 5 | 5 | 0.3 | 6 | < 0.04I | 4.3 ± 1.5 | 2/12 |
| 6 | 5 | 0.5 | 6 | < 0.04I | 3.4 ± 0.30I, E | ND |
| 7 | 5 | 0.75 | 6 | < 0.04I | 3.6 ± 0.46I, E | ND |
Rats were treated for 70 d via sc injection and serum LH and FSH concentrations were measured. Data presented as mean ± sd. I and E, Significant difference between the group and intact control group or EB control group, respectively, as analyzed by single-factor ANOVA with P < 0.05; ND, not determined.