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The P4 receptor antagonist ORG (100 nm) blocked the antagonism by P4 of E2-induced neurite outgrowth in mixed glial-neuron cocultures. A, Neurite number (total); B, neurites bigger than 20 μm in the wound zone. Results are the average of three experiments ± sem. *, P < 0.0001 for −ORG vs. +ORG.
