Fig. 1.

Task-induced activity in the default mode network. The DMN is shown in light blue. The top left image shows the medial surface right hemisphere whereas the top right image shows the lateral surface left hemisphere. The bottom left shows the lateral surface right hemisphere whereas the bottom right image shows the medial surface left hemisphere. All regions are shown in Table 1 (group differences) or Table S1 (regions without group difference effects). As indicated by the legend, superimposed red colored regions show areas within the DMN where task-induced differences distinguished depressed and control subjects. The remaining regions had no group differences but had activity decreases in the regulate condition only (yellow), in the look condition only (green), in both the regulate and look conditions (brown), or had activity increases in both the regulate and look conditions (fuschia).