Table 1.

Regions showing significant group differences in activations in the analysis of passive viewing of neutral and negative pictures (look) and regulation vs. passive viewing of negative pictures (regulate)

Region	(X, Y, Z)	No. of voxels	Look effect (dep > con), P value	Regulate effect (dep > con), P value
Decreased activity
Anterior cingulate
Dorsal BA32	−18, 18, 38	46	<0.001	<0.001
Rostral BA24	18, 19, 28	81	0.005	<0.001
Ventromedial prefrontal cortex
Medial frontal BA10	−4, 53, −3	108	<0.0001	<0.0001
Medial frontal BA10	4, 54, −8	32	0.004	<0.0001
Lateral temporal cortex
BA21	−43, −16, −5	129	<0.0001	<0.0001
BA21	−44, −15, −5	132	<0.0001	<0.0001
BA21	−52, 1, −27	92	<0.0001	<0.0001
BA21	−50, 1, −27	97	<0.0001	<0.0001
BA21	−55, −2, −21	90	<0.01	ns
Lateral parietal cortex
BA39	42, −71, 13	61	0.004	<0.001
Increased activity
Amygdala	−22, −6, −13	55	0.01*	ns
Hippocampus	19, −27, −7	73	0.009*	ns
Parahippocampal gyrus	−22, −31, −18	51	0.007	<0.001
Dorsal medial prefrontal cortex
Medial BA8	−11, 14, 50	50	0.005†	0.002

*Time frame 5–8 s, see text.

^†Dep < con.