Table 3.
Age and Multivariate Adjusted Means (95% Confidence Intervals) for Continuous Physical Function Outcome by Sleep Measures
| Grip Strength (kg) | Usual Walking Speed (m/s) | |||
|---|---|---|---|---|
| Age adjusted | Multivariate adjusted | Age adjusted | Multivariate adjusted | |
| Total Nighttime Sleep § | ||||
| ≤6 hours | 37.0 (36.5-37.5) | 37.0 (36.5-37.5) | 1.1 (1.1-1.1) | 1.1 (1.1-1.1) |
| 6-8 hours | 38.4 (38.0-38.7) | 38.4 (38.1-38.8) | 1.2 (1.2-1.3) | 1.2 (1.1-1.2) |
| ≥8 hours | 37.5 (36.5-38.5)† | 37.5 (36.5-38.5)† | 1.1 (1.1-1.2)† | 1.1 (1.1-1.2) |
| Sleep Efficiency § | ||||
| ≥80% | 38.2 (37.9-38.6) | 38.2 (37.8-38.5) | 1.2 (1.2-1.2) | 1.2 (1.1-1.2) |
| <80% | 37.1 (36.6-37.6)‡ | 37.3 (36.8-37.8)† | 1.1 (1.1-1.1)‡ | 1.1 (1.1-1.1)* |
| Sleep Latency § | ||||
| <30 min | 38.1 (37.7-38.4) | 38.0 (37.7-38.3) | 1.2 (1.2-1.2) | 1.2 (1.1-1.2) |
| ≥30 min | 37.5 (37.1-38.0) | 37.7 (37.3-38.2) | 1.1 (1.1-1.1)‡ | 1.1 (1.1-1.2) |
| WASO § | ||||
| <90 min | 38.2 (37.9-38.6) | 38.2 (37.8-38.5) | 1.2 (1.2-1.2) | 1.2 (1.1-1.2) |
| ≥90 min | 37.1 (36.7-37.6)‡ | 37.3 (36.9-37.8)† | 1.1 (1.1-1.1)‡ | 1.1 (1.1-1.1)† |
| REM | ||||
| Quartile 1 (<14.8%) | 37.2 (36.6-37.8) | 37.4 (36.8-38.0) | 1.1 (1.1-1.1) | 1.1 (1.1-1.1) |
| Quartile 2 (14.8-19.6%) | 37.9 (37.3-38.4) | 37.8 (37.2-38.3) | 1.2 (1.1-1.2) | 1.2 (1.1-1.2) |
| Quartile 3 (19.6-23.7%) | 38.6 (38.0-39.2) | 38.6 (38.0-39.1) | 1.2 (1.2-1.2) | 1.2 (1.1-1.2) |
| Quartile 4 (≥23.7%) | 38.2 (37.7-38.8)† | 38.2 (37.6-38.7)* | 1.2 (1.1-1.2)‡ | 1.2 (1.1-1.2)* |
| Respiratory Disturbance Index | ||||
| RDI <30 | 38.0 (37.7-38.3) | 38.0 (37.7-38.3) | 1.2 (1.1-1.2) | 1.2 (1.1-1.2) |
| RDI ≥30 | 37.2 (36.5-37.9)* | 37.4 (36.7-38.0) | 1.1 (1.1-1.1) ‡ | 1.1 (1.1-1.1) |
| % Sleep Time with O2<90% | ||||
| <1% | 38.3 (37.9, 38.7) | 38.2 (37.8, 38.6) | 1.2 (1.2, 1.2) | 1.2 (1.1, 1.2) |
| ≥1% | 37.5 (37.1, 37.9)† | 37.6 (37.2, 38.0)* | 1.1 (1.1, 1.1)‡ | 1.1 (1.1, 1.1)† |
*
p-trend <.05
†
p-trend <.01
‡
p-trend <.001
§
Measured by actigraphy
Wake after Sleep Onset (WASO), Rapid Eye Movement Sleep (REM), Oxygen Saturation (O2)
Multivariate adjustment includes age, BMI, clinic site, antidepressant use, hypertension, comorbid disease (history of at least one medical condition including cardiovascular disease, osteoarthritis, diabetes, COPD and Parkinson's disease), Physical Activity Scale for the Elderly, and smoking