Table 3.
Genes similarly up-regulated by oxLDL-IC and KLH-IC
| Gene | Symbol | Accession No. | Gene ID1 | Function2 |
|---|---|---|---|---|
| Heat shock 70kDa protein 1A | HSPA1A | NM_005345 | 3303 | stabilizes proteins against aggregation, protein folding, ubiquitin-proteasome pathway |
| Heat shock 70kDa protein 1B | HSPA1B | NM_005346 | 3304 | anti-apoptosis, response to unfolded protein, protein folding |
| Heat shock 70kDa protein 6 (HSP70B′) | HSPA6 | NM_002155 | 3310 | response to unfolded protein |
| DnaJ (Hsp40) homolog, subfamily B, member 1 | DNAJB1 | NM_006145 | 3337 | response to unfolded protein, protein folding, HSP binding |
| BCL2-associated athanogene 3 | BAG3 | NM_004281 | 9531 | anti-apoptosis, protein folding, modulates the activity of HSP70 class |
| Jun B proto-oncogene | JUNB | NM_002229 | 3726 | anti-apoptosis |
| Growth arrest and DNA-damage-inducible, beta | GADD45B | NM_015675 | 4616 | regulation of growth and apoptosis in response to stress |
| Immediate early response 5 | IER5 | NM_016545 | 51278 | mediates cellular response to mitogenic signals |
| SRY (sex determining region Y)-box 4 | SOX4 | BG528420 | 6659 | determination of the cell fate (death/survival) |
| Superoxide dismutase 2, mitochondrial | SOD2 | AL050388 | 6648 | response to oxidative stress |
| Dual specificity phosphatase 1 | DUSP1 | AA530892 | 1843 | response to oxidative stress |
| Mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N- acetylglucosaminyltransferase, isoenzyme A | MGAT4A | BC031487 | 11320 | carbohydrate metabolic process, cell differentiation |
| Coatomer protein complex, subunit alpha | COPA | BC037941 | 1314 | protein transport between endoplasmic reticulum and Golgi |
| yrdC domain containing | YRDC | NM_024640 | 79693 | regulates the activity of a variety of transporters |
| Oxysterol binding protein | OSBP | BC017975 | 5007 | intracellular lipid transport |
| Tumor necrosis factor (ligand) superfamily, member 9 | TNFSF9 | NM_003811 | 8744 | inflammatory response, cytokine activity |
| Interleukin 1, beta | IL1B | NM_000576 | 3553 | inflammatory response |
| v-fos FBJ murine osteosarcoma viral oncogene homolog | FOS | BC004490 | 2353 | inflammatory response, regulator of cell proliferation, differentiation, and transformation. |
| NFKB inhibitor interacting Ras-like 1 | NKIRAS1 | AI970120 | 28512 | inflammatory response, regulates the degradation of IkappaB |
| Ribosomal protein L17 | hCG_2004593 | AA522618 | 6139 | inflammatory response, signal transducer activity, regulation of I-kappaB kinase/NF-kappaB cascade |
| RNA binding motif protein 8A | RBM8A | BC017770 | 9939 | RNA splicing |
| Early growth response 1 | EGR1 | AI459194 | 1958 | regulation of transcription |
| Early growth response 2 | EGR2 | NM_000399 | 1959 | regulation of transcription |
| Oligodendrocyte transcription factor 1 | OLIG1 | AL355743 | 116448 | regulation of transcription |
| Embryonic ectoderm development | EED | AF099032 | 8726 | repression of gene activity, regulator of integrin function |
| Zinc finger protein 342 | ZNF342 | AA761573 | 162979 | regulation of transcription |
| Zinc finger protein 36, C3H type | ZFP36 | NM_003407 | 7538 | mRNA catabolism |
| Zinc finger, AN1-type domain 2A | ZFAND2A | AI984061 | 90637 | binding to metal ions |
| Dual specificity phosphatase 2 | DUSP2 | NM_004418 | 1844 | MAPK signaling pathway |
| Regulator of G-protein signalling 2, 24kDa | RGS2 | NM_002923 | 5997 | cell cycle, regulation of G-protein coupled receptor protein |
| Myosin regulatory light chain interacting protein | MYLIP | NM_013262 | 29116 | cell motility, protein ubiquitination |
1
NCBI Entrez Gene ID number
2
based on information from GO biological process annotations and PubMed.