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. Author manuscript; available in PMC: 2010 Feb 1.
Published in final edited form as: Atherosclerosis. 2008 May 28;202(2):394–404. doi: 10.1016/j.atherosclerosis.2008.05.032

Table 4.

Genes uniquely regulated by oxLDL

Gene Symbol Accession No. Gene ID1 Function2 FC3vs PBS FC vs oxLDL-IC FC vs KLH-IC
Interferon-induced protein
with tetratricopeptide repeats 1
IFIT1 NM_001548 3434 immune response −2.58 −3.77 −3.25
Src-like-adaptor SLA U44403 6503 intracellular signaling cascade −2.45 −2.72 −2.32
Target of EGR1, member 1 (nuclear) TOE1 NM_025077 114034 growth inhibitory activity −1.93 −2.45 −2.15
AHA1, activator of heat
shock 90kDa protein ATPase
AHSA2 AI831431 130872 co-chaperone, response to unfolded protein −3.20 −2.35 −1.87
Phosphoinositide-3-kinase,
regulatory subunit 3 (p55, Gamma)
PIK3R3 BE622627 8503 modulates the activity of the enzyme phosphatidylinositol 3-kinase activity −1.89 −1.76 −2.31
Zinc finger protein 697 ZNF697 AW003092 90874 regulation of transcription 1.85 2.09 2.08
Oxidative stress induced
growth inhibitor 1
OSGIN1 NM_013370 29948 growth inhibition, cell death 2.54 2.57 2.58
Estrogen-responsive B box Protein TRIM16 NM_006470 10626 enhancing the alternative
secretion pathway of IL-1beta
4.26 2.62 2.76
Ferritin, heavy polypeptide 1 FTH1 AA083483 2495 inhibition of proliferation, ferric iron binding 3.23 3.40 3.92
Sulfiredoxin 1 homolog SRXN1 AL121758 140809 oxidoreductase activity 3.26 3.49 3.56
Solute carrier family 7,
(cationic amino acid transporter,
y+ system) member 11
SLC7A11 AB040875 23657 amino acid transport 3.15 4.04 3.84
Adipose differentiation-related Protein ADFP BC005127 123 long-chain fatty acid transport, sequestering of lipid 4.20 4.42 4.42
Heme oxygenase (decycling) 1 HMOX1 NM_002133 3162 oxidoreductase activity, iron ion binding 95.67 58.49 25.90
1

NCBI Entrez Gene ID number

2

based on information from GO biological process annotations and PubMed.

3

FC, fold change