Figure 5.

Ribbon diagrams showing bonding-stabilizing interactions involving loop β5–α6 (residues 197–210) in its ‘open’ conformation. (a) A Co²⁺ ion (Co4, shown as a dark blue sphere) is bound by His203 and Asp205; residues 201–204 also participate in a hydrogen-bond network with residues 357 and 386–387 from the C-terminal domain. (b) Hydrogen-bond interactions between glycerol and residues lining the cavity created by the movement of loop β5–α6 in MtFPGS. Water molecules are shown as red spheres.