Figure 2.
Correlation between miRNA microarray and qRT-PCR expression levels. The miRNA microarray contained 170/183 miRNA tested by qRT-PCR. Low Ct values (x-axis), obtained by qRT-PCR, correlate with high signal intensity (y-axis) observed with microarray. The high correlation coefficient (r2) indicates a positive relation between low Ct values and high signal intensity. Both platforms show the same miRNA abundantly expressed in HL (open triangles). MiRNA differentially expressed between cHL and CB and cHL and PMBL (open squares) do not deviate from this correlation. For some miRNA, no expression was observed by qRT-PCR (Ct value of 40), whereas low/average expression was observed on the microarray.