Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2009 Feb 6;5(2):e1000372. doi: 10.1371/journal.pgen.1000372

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Dowling et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

(A) Representative myofibers immunostained with anti-PI3P. Perinuclear staining of PI3P in myotubularin morphant myofibers is much more abundant than in control myofibers (arrows). There is also a modest increase in membrane localized PI3P (*). Scale bar = 10 mm. (B) Quantitation of PI3P immunofluorescence. PI3P intensity measured over a uniform perinuclear area (see methods for details) and was 83.7+/−7.8 pixels for control morphants and 135.5+/−3.3 for myotubularin morphants (3 trials; p = 0.0027). This represented a 1.6× increase in PI3P staining intensity.