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Localization of general transcription factors (NF-κB, c-Fos, c-Jun), HSP-70, and HO-1, at the start and end HMGCR exons. I/R induced significant increases of each protein at both HMGCR exons 1 and 19, compared to control kidneys. The absolute levels were consistently greater at the start versus the end exon (as would be expected with gene transcription).
