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Histone variant H2A.Z levels and H3 histone modifications at the HMGCR promoter, and along the gene. I/R caused a twofold to fourfold increase in the amounts of H2A.Z variant and of H3K4m3 at all assessed sites. H3 lysine 19 acetylation was also increased at exons 1 and 19 (but not at the promoter).
