Table 3.

Pol II, Transcription Factors, Heat Shock Proteins, and Histone Modifications/Variants in HMGCR Flanking Regions (±5 kb)

HMGCR flanking regions (±5 kb)	Contralateral kidney	72 hours I/R
Pol II
−5 kb	0.29 ± 0.02	0.24 ± 0.03 (NS)
+5 kb	0.26 ± 0.06	0.31 ± 0.05 (NS)
SREBP-1
−5 kb	0.067 ± 0.01	0.064 ± 0.006 (NS)
+5 kb	0.06 ± 0.01	0.052 ± 0.006 (NS)
SREBP-2
−5 kb	0.05 ± 0.005	0.049 ± 0.01 (NS)
+5 kb	0.052 ± 0.007	0.055 ± 0.02 (NS)
NF-κB
−5 kb	0.26 ± 0.05	0.26 ± 0.05 (NS)
+5 kb	0.20 ± 0.01	0.18 ± 0.01 (NS)
c-Fos
−5 kb	0.12 ± 0.01	0.14 ± 0.01 (NS)
+5 kb	0.11 ± 0.01	0.14 ± 0.01 (NS)
c-Jun
−5 kb	0.04 ± 0.005	0.04 ± 0.005 (NS)
+5 kb	0.03 ± 0.005	0.03 ± 0.005 (NS)
HSP-70
−5 kb	0.08 ± 0.01	0.09 ± 0.01 (NS)
+5 kb	0.03 ± 0.005	0.03 ± 0.005 (NS)
HO-1
−5 kb	0.06 ± 0.005	0.05 ± 0.005 (NS)
+5 kb	0.03 ± 0.05	0.03 ± 0.005 (NS)
H2A.Z
−5 kb	0.14 ± 0.01	0.12 ± 0.01 (NS)
+5 kb	0.10 ± 0.01	0.11 ± 0.01 (NS)
H3K4m3
−5 kb	6.5 ± 0.4	6.5 ± 0.3 (NS)
+5 kb	6.0 ± 0.02	6.3 ± 0.03 (NS)
H3K9Ac
−5 kb	0.08 ± 0.01	0.09 ± 0.01 (NS)
+5 kb	0.07 ± 0.01	0.08 ± 0.01 (NS)

Values are percent of DNA input. No significant differences were observed between control (contralateral) and postischemic kidney samples.