Table 1.
Chimeric mice | Fuc-T−/−GFP+ → LDLR−/− | GFP+ → LDLR−/− | GFP+ → Fuc-T−/−LDLR−/− |
---|---|---|---|
Week 0 | 221 ± 12 mg/dl, n = 14 | 245 ± 8 mg/dl, n = 14 | 260 ± 7 mg/dl, n = 13 |
Week 4 | 886 ± 44 mg/dl, n = 14 | 1027 ± 70 mg/dl, n = 14 | 1138 ± 110 mg/dl, n = 13 |
Week 8 | 816 ± 35 mg/dl, n = 14 | 915 ± 47 mg/dl, n = 14 | 1347 ± 78 mg/dl, n = 13* |
Week 12 | 1115 ± 53 mg/dl, n = 14 | 1196 ± 77 mg/dl, n = 14 | 1268 ± 68 mg/dl, n = 13 |
All data are shown as mean ± SEM. *P < 0.05 as determined by two-way analysis of variance followed by Bonferroni’s post-test.