Figure 3.  .

Compliance testing via 24-h urine-creatine measures.Creatine was measured in 24-hour urine collections at baseline, three and nine months. The creatine treatment group had a significant increase in measured creatine, as expected, compared with the placebo group. This indicator of compliance with assigned treatment group revealed significant compliance to the protocol, despite the availability of creatine in the community (see text). Creatine vs. placebo at baseline, p=0.367 Creatine vs. placebo at three months, p<0.00001 Creatine vs. placebo at nine months, p<0.00001