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Endocrine Functions of CL in Pten CKO Mice
Levels of serum estradiol (A) and progesterone (B) were not different between control and Pten CKO mice after eCG/hCG treatments. At d 2 after hCG, CYP11A1 was expressed at high level in CL (C and D) but declined at d 5 regardless of genotype (E and F). Conversely, 20α-HSD was expressed in a reciprocal manner to CYP11A1, in both wild (G and I) and Pten CKO ovaries (H and J). WT, Wild type.
