Table 2.
Serum Hormone Profiles of Rb cKO Females
| Genotype | FSH (ng/ml) | LH (ng/ml) | E2 (pg/ml) |
|---|---|---|---|
| 3 Months old | |||
| Rbflox/− | 4.42 ± 1.30 | 0.28 ± 0.08 | 24.02 ± 6.72 |
| Rb cKO | 5.95 ± 0.78 | 0.14 ± 0.04 | 25.02 ± 9.94 |
| 6 Months old | |||
| Rbflox/− | 5.15 ± 0.54 | ND | 33.075 ± 13.9 |
| Rb cKO | 6.50 ± 1.30 | ND | 18.37 ± 4.24 |
| 8 Months old | |||
| Rbflox/− | 7.61 ± 1.08 | 0.12 ± 0.02 | 32.63 ± 3.27 |
| Rb cKO | 6.13 ± 1.30 | 0.09 ± 0.04 | 34.95 ± 9.7 |
Results are shown as the mean ± sem. Data were analyzed using the nonparametric Mann-Whitney U test. No statistically significant differences were found between Rbflox/−, Amhr2Cre− (Rbflox/−) and Rbflox/−, Amhr2Cre+ (Rb cKO ). E2, 17β -Estradiol; ND, not determined.