Table 3.

Serum opsonophagocytic killing of S. pneumoniae^*

		Serotype
		6B	14	19F	23F
Group 1 (PPV followed by PCV)
Baseline	n†=28	93	113	22	15
4–8 wk post-PPV	n=31	159	565	54	51
6 mo post-PPV	n=20	20	128	12	8
4–8 wk post-PCV	n=20	53	545	27	57
6 mo post-PCV	n=14	16	220	11	29
Group 2 (PCV followed by PPV)
Baseline	n=22	30	152	16	21
4–8 wk post-PCV	n=30	135	379	39	200
6 mo post-PCV	n=17	60	321	21	170
4–8 wk post-PPV	n=17	351	554	85	309
6 mo post-PPV	n=11	27	236	23	37

^*Geometrical mean for opsonophagocytic killing (OPK) index at each stage of study for patients who received PPV followed by PCV (Group 1) or PCV followed by PPV (Group 2).

^†n= numbers of subjects at each time point. Fewer sera were included at each time point in this assay than in the ELISA, because they could not be studied due to presence of antibiotics.