Figure 3. The Dot/Icm translocation apparatus.
Depicted are the presumed locales and topological relationships of the various Dot/Icm components in the L. pneumophila envelope based on a study of the stability of individual proteins in the presence of defined deletion mutations46. Individual letters represent Dot protein names whereas letters preceded by an āiā indicated Icm protein names. See text for further details of the individual Dot/Icm components.