Fig. 6. Predicted Secondary Structures of Mitochondrial tRNA-Arg.
A) The tRNA-Arg structure of C57BL/6J mouse. The DHU loop consists of 5 adenine nucleotides. B) The number of adenine nucleotide insertions in the poly(A) tract affects the size of the DHU loop. The adenine nucleotide insertions of 1, 2, 3, 4, and 5 nucleotides increase the size of the DHU loop to 6, 7, 8, and 9 nucleotides, respectively. Different poly(A) length variants are found in different murine strains (Table 2). C) However, the insertion of 4 adenine nucleotides observed in the MRL mouse (12 A in the poly(A) stretch) may result in the formation of an additional, not less stable, cloverleaf structural variant, which has the DHU loop consisting of 5 adenine nucleotides, as in the C57BL/6J mouse, while the stems of anticodon and T-arms are longer and shorter, respectively.