Table 2.
Adverse events related to vaccine and IL-2
| Vaccine-related AEs | Maximum Grade | Patients | ||
| System | Adverse Events | N = 25 | % | |
| Constitutional | Fever | 1 | 8 | 32 |
| Pain at injection site | 1 | 4 | 16 | |
| Injection site reaction | 1 | 3 | 12 | |
| Myalgia | 1 | 1 | 4 | |
| Chills | 1 | 1 | 4 | |
| IL-2-related AEs | ||||
| Cardiovascular | Cardiopulmonary arrest | 4 | 1 | 4 |
| Elevated troponin | 4 | 1 | 4 | |
| Hypotension | 4 | 9 | 36 | |
| Ventricular tachycardia | 3 | 1 | 4 | |
| Acidosis | 4 | 1 | 4 | |
| Electrolyte | Hyperglycemia | 3 | 4 | 16 |
| Hypocalcemia | 3 | 1 | 4 | |
| Hyponatremia | 3 | 11 | 44 | |
| Hypophosphatemia | 3 | 3 | 12 | |
| Gastro-intestinal | Ischemic bowel | 4 | 1 | 4 |
| Hematologic | Anemia | 3 | 2 | 8 |
| Neutropenia | 3 | 1 | 4 | |
| Thrombocytopenia | 3 | 4 | 16 | |
| Hepatic | Elevated transaminases | 3 | 1 | 4 |
| Hyperbilirubinemia | 3 | 3 | 12 | |
| Neurologic | Confusion | 3 | 3 | 12 |
| Syncope | 3 | 2 | 8 | |
| Pulmonary | Dyspnea | 3 | 1 | 4 |
| Renal | Elevated creatinine | 3 | 22 | 88 |
| Oliguria | 3 | 2 | 8 | |
| Systemic | Fatigue | 3 | 1 | 4 |