Figure 1.

Outline of data flow. ContDist is composed of three separate layers along with a MySQL database. The top layer (A) corresponds to the web interface where the user input is handled, the available promoter properties are retrieved from the MySQL database and the information is parsed to the middle layer (B). The middle layer (B) performs all mappings, retrieves the values of the promoter properties to be statistically analyzed, applies the appropriate statistical tests and parses the data to the bottom layer (C). The bottom layer generates a HTML-based output describing the statistical differences detected for the chosen annotations in the input data. Dashed arrows correspond to the communication of the layers with the MySQL database whereas plain arrows correspond to the dataflow between layers.