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. Author manuscript; available in PMC: 2009 Jan 27.
Published in final edited form as: J Med Chem. 2007 Mar 17;50(8):1799–1809. doi: 10.1021/jm0612463

Figure 1.

Figure 1

Non-peptidic δ opioid ligands used in the development of the quantitative efficacy and affinity models. The pharmacophore groups A in green, B in red and N in blue. Compounds 8 and 9 were included only for affinity modeling and compounds 10 - 13 were used as external tests for efficacy prediction.