Table 3.
Multivariatea Relative Risk of Lung Cancer According to Quintile of Intake of Selected Botanical Groups, NIH-AARP Diet and Health Study, 1995–2003
Botanical Group and Sex | Quintile of intake |
P for Trend | |||||||||||||||||
1 b |
2 |
3 |
4 |
5 |
|||||||||||||||
No. of Cases | Intakec | No. of Cases | Intake | RR | 95% CI | No. of Cases | Intake | RR | 95% CI | No. of Cases | Intake | RR | 95% CI | No. of Cases | Intake | RR | 95% CI | ||
Cucurbitaceae | |||||||||||||||||||
Men | 932 | 0.003 | 803 | 0.01 | 0.97 | 0.88, 1.07 | 717 | 0.03 | 0.98 | 0.88, 1.08 | 728 | 0.07 | 1.04 | 0.94, 1.14 | 654 | 0.20 | 0.95 | 0.86, 1.05 | 0.50 |
Women | 564 | 0.006 | 439 | 0.02 | 0.92 | 0.81, 1.04 | 401 | 0.05 | 0.92 | 0.81, 1.05 | 378 | 0.13 | 0.92 | 0.81, 1.05 | 419 | 0.33 | 1.05 | 0.92, 1.19 | 0.14 |
Musaceae | |||||||||||||||||||
Men | 1,003 | 0.01 | 849 | 0.05 | 1.00 | 0.91, 1.09 | 722 | 0.14 | 0.97 | 0.88, 1.07 | 645 | 0.29 | 0.94 | 0.85, 1.04 | 615 | 0.53 | 0.97 | 0.87, 1.08 | 0.42 |
Women | 604 | 0.01 | 480 | 0.07 | 0.98 | 0.86, 1.10 | 343 | 0.18 | 0.80 | 0.70, 0.91 | 378 | 0.35 | 0.94 | 0.83, 1.08 | 396 | 0.63 | 1.01 | 0.88, 1.15 | 0.73 |
Rosaceae | |||||||||||||||||||
Men | 1,154 | 0.03 | 824 | 0.09 | 0.94 | 0.85, 1.02 | 699 | 0.18 | 0.92 | 0.83, 1.01 | 654 | 0.35 | 0.97 | 0.88, 1.07 | 503 | 0.72 | 0.82 | 0.73, 0.91 | 0.002 |
Women | 670 | 0.05 | 481 | 0.14 | 1.00 | 0.89, 1.12 | 403 | 0.27 | 1.01 | 0.89, 1.14 | 334 | 0.49 | 0.93 | 0.81, 1.07 | 313 | 0.94 | 0.97 | 0.85, 1.12 | 0.52 |
Rutaceae | |||||||||||||||||||
Men | 1,068 | 0.04 | 808 | 0.19 | 0.99 | 0.91, 1.09 | 715 | 0.43 | 0.97 | 0.88, 1.07 | 635 | 0.73 | 0.95 | 0.86, 1.05 | 608 | 1.35 | 0.99 | 0.89, 1.10 | 0.68 |
Women | 633 | 0.05 | 432 | 0.21 | 0.90 | 0.79, 1.01 | 369 | 0.50 | 0.86 | 0.75, 0.98 | 414 | 0.84 | 1.00 | 0.88, 1.13 | 353 | 1.51 | 0.91 | 0.79, 1.04 | 0.55 |
Vitaceae | |||||||||||||||||||
Men | 1,045 | 0.002 | 808 | 0.01 | 0.95 | 0.87, 1.05 | 689 | 0.03 | 0.93 | 0.84, 1.03 | 672 | 0.06 | 0.97 | 0.87, 1.07 | 620 | 0.18 | 0.94 | 0.85, 1.04 | 0.47 |
Women | 567 | 0 | 434 | 0.02 | 0.93 | 0.82, 1.05 | 408 | 0.04 | 0.95 | 0.84, 1.08 | 408 | 0.08 | 1.03 | 0.91, 1.17 | 384 | 0.29 | 0.99 | 0.86, 1.13 | 0.70 |
Chenopodiaceae | |||||||||||||||||||
Men | 957 | 0 | 675 | 0.006 | 0.91 | 0.83, 1.01 | 824 | 0.01 | 1.03 | 0.94, 1.14 | 738 | 0.04 | 0.97 | 0.88, 1.07 | 640 | 0.13 | 0.94 | 0.85, 1.04 | 0.33 |
Women | 474 | 0 | 455 | 0.01 | 1.02 | 0.89, 1.16 | 440 | 0.03 | 1.00 | 0.88, 1.14 | 432 | 0.06 | 1.02 | 0.89, 1.16 | 400 | 0.21 | 1.00 | 0.87, 1.15 | 0.93 |
Compositae | |||||||||||||||||||
Men | 1,026 | 0.01 | 824 | 0.06 | 0.98 | 0.90, 1.08 | 720 | 0.14 | 0.96 | 0.87, 1.05 | 657 | 0.26 | 0.95 | 0.86, 1.05 | 607 | 0.63 | 0.92 | 0.83, 1.02 | 0.09 |
Women | 543 | 0.02 | 424 | 0.09 | 0.89 | 0.78, 1.01 | 413 | 0.21 | 0.94 | 0.83, 1.07 | 395 | 0.39 | 0.93 | 0.81, 1.06 | 426 | 0.91 | 1.02 | 0.89, 1.16 | 0.29 |
Convolvulaceae | |||||||||||||||||||
Men | 897 | 0 | 808 | 0.005 | 1.00 | 0.91, 1.10 | 799 | 0.01 | 0.98 | 0.89, 1.08 | 695 | 0.03 | 0.91 | 0.82, 1.00 | 635 | 0.07 | 0.86 | 0.75, 0.96 | 0.0008 |
Women | 529 | 0 | 432 | 0.009 | 0.88 | 0.77, 1.00 | 416 | 0.02 | 0.88 | 0.77, 1.00 | 421 | 0.04 | 0.93 | 0.82, 1.06 | 403 | 0.11 | 0.95 | 0.83, 1.09 | 0.77 |
Cruciferae | |||||||||||||||||||
Men | 1,024 | 0.03 | 839 | 0.08 | 0.97 | 0.89, 1.07 | 719 | 0.15 | 0.91 | 0.83, 1.00 | 641 | 0.25 | 0.90 | 0.81, 0.99 | 611 | 0.50 | 0.92 | 0.83, 1.02 | 0.09 |
Women | 522 | 0.06 | 439 | 0.14 | 0.96 | 0.84, 1.09 | 417 | 0.24 | 0.99 | 0.87, 1.13 | 427 | 0.39 | 1.06 | 0.93, 1.20 | 396 | 0.77 | 1.00 | 0.87, 1.14 | 0.65 |
Gramineae | |||||||||||||||||||
Men | 924 | 0.009 | 781 | 0.03 | 0.93 | 0.85, 1.03 | 777 | 0.05 | 0.98 | 0.89, 1.08 | 661 | 0.08 | 0.86 | 0.78, 0.95 | 691 | 0.16 | 0.96 | 0.87, 1.06 | 0.30 |
Women | 525 | 0.008 | 460 | 0.03 | 0.97 | 0.85, 1.09 | 443 | 0.05 | 0.99 | 0.87, 1.12 | 407 | 0.09 | 0.95 | 0.84, 1.09 | 366 | 0.17 | 0.91 | 0.79, 1.04 | 0.16 |
Legumes | |||||||||||||||||||
Men | 918 | 0.08 | 808 | 0.17 | 0.98 | 0.89, 1.07 | 716 | 0.27 | 0.90 | 0.81, 0.99 | 733 | 0.40 | 0.98 | 0.89, 1.08 | 659 | 0.69 | 0.92 | 0.83, 1.02 | 0.16 |
Women | 512 | 0.09 | 483 | 0.19 | 1.07 | 0.94, 1.21 | 414 | 0.30 | 0.95 | 0.83, 1.08 | 380 | 0.45 | 0.93 | 0.81, 1.06 | 412 | 0.81 | 1.07 | 0.94, 1.22 | 0.65 |
Solanaceae | |||||||||||||||||||
Men | 911 | 0.07 | 766 | 0.15 | 0.97 | 0.88, 1.07 | 734 | 0.23 | 0.98 | 0.89, 1.08 | 674 | 0.34 | 0.94 | 0.85, 1.03 | 749 | 0.60 | 1.02 | 0.93, 1.13 | 0.60 |
Women | 472 | 0.08 | 428 | 0.17 | 0.98 | 0.86, 1.11 | 411 | 0.27 | 1.00 | 0.87, 1.14 | 423 | 0.40 | 1.04 | 0.91, 1.19 | 467 | 0.71 | 1.11 | 0.97, 1.27 | 0.04 |
Umbelliferae | |||||||||||||||||||
Men | 1,070 | 0.005 | 848 | 0.02 | 0.97 | 0.89, 1.07 | 703 | 0.03 | 0.89 | 0.80, 0.98 | 655 | 0.07 | 0.91 | 0.83, 1.01 | 558 | 0.21 | 0.86 | 0.78, 0.96 | 0.01 |
Women | 593 | 0.008 | 475 | 0.03 | 0.96 | 0.85, 1.08 | 416 | 0.06 | 0.92 | 0.81, 1.04 | 388 | 0.13 | 0.93 | 0.82, 1.06 | 329 | 0.36 | 0.92 | 0.80, 1.06 | 0.38 |
Abbreviations: CI, confidence interval; NIH, National Institutes of Health; RR, relative risk.
Adjusted for age, energy intake, race, education, body mass index, smoking status, smoking dose, time since quitting smoking, alcohol intake, physical activity, and family history of any cancer.
Reference category (RR = 1).
Median number of servings/1,000 kcal/day.