Table 1.
Mean values of proton T2 relaxation times at 3 T (in milliseconds ± SEM) of N-acetylaspartate (NAA), creatine (Cr) and choline (Cho) in the various GM and WM brain regions indicated (cf. Figs. 1 and 3) in 4 adolescents, 8 young adults, 2 middle-aged, and 6 elderly subjects. CC – corpus callosum.
| GM: | T2 NAA (ms) | T2 Cr (ms) | T2 Cho (ms) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Adolescent | Young | Middle- aged | Elderly | Adolescent | Young | Middle- aged | Elderly | Adolescent | Young | Middle- aged | Elderly | |
| Caudate | 300±23 | 306±19 | 203±45 | 280±33 | 184±10 | 194±6 | 147±36 | 184±28 | 258±11 | 211±4 | 254±0 | 240±11 |
| Thalamus | 277±13 | 267±14 | 288±44 | 285±15 | 162±17 | 152±4 | 152±4 | 164±5 | 268±21 | 241±12 | 241±25 | 235±18 |
| Cingulate gyrus | 421±40 | 277±11 | 271±9 | 215±18 | 162±9 | 160±5 | 173±33 | 147±6 | 278±18 | 255±10 | 324±45 | 291±26 |
| Globus pallidus | 275±5 | 252±8 | 219±24 | 255±8 | 144±9 | 141±5 | 149±27 | 145±9 | 240±12 | 191±11 | 181±5 | 206±9 |
| Putamen | 310±26 | 263±13 | 205±0 | 223±15 | 161±9 | 157±6 | 151±11 | 132±9 | 271±12 | 216±15 | 196±2 | 206±16 |
| GM average | 301±30 | 269±7 | 247±28 | 259±13 | 162±7 | 156±7 | 153±7 | 154±8 | 263±7 | 226±9 | 229±40 | 229±14 |
| WM: | ||||||||||||
| Splenium of CC | 405±32 | 375±24 | 327±19 | 314±15 | 205±10 | 164±4 | 183±14 | 193±12 | 292±9 | 236±22 | 207±22 | 266±31 |
| Genu of CC | 361±29 | 326±21 | 405±74 | 310±55 | 251±36 | 202±17 | 175±15 | 162±10 | 279±17 | 247±18 | 233±26 | 260±32 |
| Centrum semiovale | 458±11 | 397±16 | 401±22 | 391±13 | 190±2 | 187±2 | 186±11 | 186±7 | 278±10 | 245±6 | 258±22 | 259±15 |
| Occipital | 461±20 | 366±13 | 493±81 | 360±18 | 188±11 | 175±5 | 197±32 | 169±10 | 289±21 | 228±8 | 272±23 | 235±16 |
| Corona radiata | 400±21 | 362±21 | 389±67 | 383±22 | 180±7 | 173±5 | 180±21 | 174±8 | 256±17 | 234±7 | 269±43 | 251±10 |
| WM average | 428±21 | 374±9 | 408±42 | 371±16 | 192±14 | 179±5 | 185±6 | 178±5 | 274±7 | 238±7 | 259±19 | 253±5 |
| GM+WM | 365±36 | 338±19 | 345±71 | 322±25 | 177±15 | 172±7 | 172±13 | 167±8 | 268±8 | 234±7 | 247±30 | 242±11 |
| GM+WM average | 343 | 172 | 248 | |||||||||