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. 2008 Dec 22;8:384. doi: 10.1186/1471-2407-8-384

Table 2.

Twenty genes that were identified as upregulated in tumors of the high SUV group compared with those of the low SUV group

Rank Symbol Gene name Genbank Accession No. High/Low ratioa) Function
1 CENPF centromere protein F (mitosin) NM016343 3.66 cell-cycle regulation
2 CDC6 cell division cycle 6 NM001254 3.36 cell-cycle regulation
3 gtf2b general transcription factor IIB M76766 2.79 transcription initiation
4 Fgr Gardner-Rasheed feline sarcoma viral oncogene homolog NM005248 2.49 mast cell activation
5 GAPDHS glyceraldehyde-3-phosphate_dehydrogenase NM002046 2.18 carbohydrate metabolism
6 Oaz1 ornithine decarboxylase 1 NM002539 2.14 regulation of polyamine synthesis
7 ACTA1 actin, alpha 2, smooth muscle, aorta NM001613 2.1 cell motility, structure
8 KRT5 keratin 5 NM000424 2.05 type 2 cytokeratine
9 RCC1 chromosome condensation 1 NM001269 2.03 cell-cycle regulation
10 BAK1 BCL2-antagonist/killer 1 NM001188 1.96 anti- or pro-apoptotic regulators
11 MMP9 matrix metalloproteinase 9 NM004994 1.95 embryonic development and tissue remodeling
12 MAP2K5 mitogen-activated protein kinase kinase 5 NM002757 1.94 Kinase related to signal cascade
13 MAP2K2 mitogen-activated protein kinase kinase 2 NM030662 1.93 Kinase related to signal cascade
14 Litaf LPS-induced TNF-alpha factor NM004862 1.9 proinflammatory cytokine
15 COL7A1 collagen, type VII, alpha 1 NM000094 1.85 epithelial adhesion complex
16 HRMT1L2 HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 2 NM001536 1.84 catalyzes protein methyl-transferase modification
17 CXCL13 small inducible cytokine B subfamily, member 13 NM006419 1.82 migration of B lymphocytes
18 PLAU plasminogen activator, urokinase NM002658 1.78 serine protease
19 CDC37 cell division cycle 37 NM007065 1.77 cell-cycle regulation
20 Pax paxillin NM002859 1.74 cell adhesion of the extracellular matrix

a) High/low ratio; the ratio of the quantitative value of the gene expression in tumors of the high SUV group to that in tumors of the low SUV group.