Table 3.
Comparision of clinicopathological features of patients and immunohistochemical results of biomarkers between the low SUV group and the high SUV group in 47 cases of node-negative breast cancer
| Parameters | High SUV group (n = 27) |
Low SUV group (n = 20) |
p-value | |
| SUV | Ave± SD | 7.8± 3.4 | 2.2± 1.0 | <0.0001 |
| Age | Ave± SD | 55.6± 10.1 | 53.2± 10.0 | 0.42 |
| Tumor size | Ave± SD | 3.1± 2.1 | 2.4± 2.9 | 0.33 |
| Nuclear grade | 1 and 2 | 8 | 15 | 0.004 |
| 3 | 19 | 5 | ||
| ER | <10% | 11 | 3 | 0.06 |
| 10% ≦ | 16 | 17 | ||
| HER2 | 0,1+,2+ (FISH-) | 20 | 18 | 0.17 |
| 3+ or FISH+ | 7 | 2 | ||
| CENP-F | Positive | 20 | 9 | 0.04 |
| Negative | 7 | 11 | ||
| n-CDC6 | Positive | 13 | 10 | 0.9 |
| Negative | 10 | 10 | ||
| c-CDC6 | Positive | 9 | 7 | 0.9 |
| Negative | 18 | 13 | ||
| Ki67 | Positive | 25 | 12 | 0.02 |
| Negative | 2 | 8 | ||
| p53 | Positive | 9 | 2 | 0.06 |
| Negative | 18 | 18 | ||
| Molecular subtypes | Luminal A | 16 | 17 | 0.05 |
| HER2 | 7 | 2 | ||
| Triple negative | 4 | 1 |
Abbreviations; SUV, Standardized uptake value; ER, Estrogen receptor; HER2, c-erbB2; FISH, Fluorescence in situ hybridization; SD, standard deviation; CENP-F, Centromere protein-F; SUV, Standardized uptake value; n-CDC6, nuclear staining of Cell devision cycle 6; c-CDC6, cytoplasmic staining of Cell devision cycle 6