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. 2008 Dec 31;8:120. doi: 10.1186/1471-213X-8-120

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Copyright © 2008 Ding et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Statin treatment reduces PGC survival. PGCs were counted in tissue cultured in (A) mevinolin (B) atorvastatin or (C) simvastatin. Average percent survival ± s.e.m. is shown. n = number of slices. "* " = groups that differed from controls. (F < 0.05 Analysis of Variance from Walpole and Meyer with Fishers least significance post test). (D) A control slice after culture. (E) A slice treated with 100 μM atorvastatin. Note sloughing of somatic cells from the surface of the slice. Scale bar is 100 μm.