Table 3.

Y. pseudotuberculosis IP32953 pYV plasmid-harbored genes that are transcriptionally regulated by growth medium and/or temperature.

			Fold ratio in gene transcription (p-value)
Gene designation	Genoscript spot ID	Gene product/function	Human plasma/Luria Bertani Broth		37°C/28°C
pYV0013	pCD1-yadA	hypothetical protein	13.528	(< 0.001)	1.577	(0.046)
pYV0014	pCD1-AAC62595	possible transposase remnant	1.789	(0.025)	1.884	(0.016)
pYV0017	pCD1-tnpR	putative resolvase	0.341	(< 0.001)
pYV0020	pCD1-sycH	putative YopH targeting protein	5.088	(< 0.001)	2.715	(< 0.001)
pYV0024	pCD1-sycE	putative YopE chaperone	5.781	(< 0.001)	2.403	(0.005)
pYV0040	pCD1-yopK/yopQ	Yop targeting protein YopK, YopQ			1.666	(0.019)
pYV0047	pCD1-yopM	putative targeted effector protein	3.468	(< 0.001)	2.252	(0.002)
pYV0054	pCD1-yopD	putative Yop negative regulation/targeting component	2.933	(< 0.001)	2.211	(0.004)
pYV0055	pCD1-yopB	putative Yop targeting protein	2.816	(< 0.001)	2.196	(< 0.001)
pYV0056	pCD1-lcrH	low calcium response protein H	3.522	(< 0.001)	1.851	(0.021)
pYV0057	pCD1-lcrV	putative V antigen, antihost protein/regulator	1.904	(< 0.001)	1.637	(0.003)
pYV0058	pCD1-lcrG	putative Yop regulator	1.713	(0.014)
pYV0059	pCD1-lcrR	hypothetical protein LcrR	1.469	(0.001)	1.849	(< 0.001)
pYV0062	pCD1-yscX	putative type III secretion protein	1.629	(0.009)	1.533	(0.020)
pYV0065	pCD1-yopN	putative membrane-bound Yop targeting protein	2.612	(< 0.001)	1.549	(0.049)
pYV0067	pCD1-yscN	putative Yops secretion ATP synthase	2.856	(< 0.001)	1.717	(0.002)
pYV0068	pCD1-yscO	putative type III secretion protein	3.088	(< 0.001)
pYV0069	pCD1-yscP	putative type III secretion protein			1.593	(0.018)
pYV0070	pCD1-yscQ	putative type III secretion protein	1.635	(0.026)
pYV0071	pCD1-yscR	putative Yop secretion membrane protein	1.949	(0.012)
pYV0072	pCD1-yscS	putative type III secretion protein	2.331	(< 0.001)	1.897	(0.002)
pYV0075	pCD1-virG	putative Yop targeting lipoprotein	1.957
pYV0076	pCD1-lcrF/virF	putative thermoregulatory protein	1.441	(0.042)
pYV0078	pCD1-yscB	hypothetical protein	3.038	(0.002)
pYV0079	pCD1-yscC	putative type III secretion protein	2.384	(0.001)	2.713	(< 0.001)
pYV0080	pCD1-yscD	putative type III secretion protein	2.542	(< 0.001)	1.990	(0.005)
pYV0081	pCD1-yscE	putative type III secretion protein	2.711	(0.001)	1.809	(0.032)
pYV0082	pCD1-yscF	putative type III secretion protein	2.117	(0.017)
pYV0083	pCD1-yscG	putative type III secretion protein	2.463	(< 0.001)
pYV0085	pCD1-yscI	putative type III secretion protein	1.864	(0.003)
pYV0089	pCD1-yscM	putative type III secretion regulatory protein	0.679	(0.036)