Table 1.
Characteristics of participants younger than 65 years
| n=1 | n=1 | n=243 | n=5 | n=5 | ||
|---|---|---|---|---|---|---|
| Overt Hypothyroidism | Subclinical Hypothyroidism | Euthyroidism | Subclinical Hyperthyroidism | Overt Hyperthyroidism | P* | |
| Age (years) # | 62.52 | 38.73 | 44.35 ± 13.02 | 47.64 ± 16.20 | 39.68 ± 16.08 | 0.52 |
| Sex female (%) | 100 | 0 | 53.91 | 80.00 | 60.00 | 0.77 |
| Education (years) # | 5.0 | 14.0 | 10.78 ± 4.47 | 7.80 ± 3.56 | 11.60 ± 5.36 | 0.82 |
| Mini-Mental State Examination corrected score (0-30)# | 29.00 | 29.00 | 28.36 ± 1.82 | 28.20 ± 2.05 | 29.40 ± 0.89 | 0.52 |
| TSH (mUI/L) # | 50.3 | 5.26 | 1.71 ± 0.80 | 0.40 ± 0.04 | 0.16 ± 0.12 | <.0001 |
| FT4 (ng/dL) # | 0.64 | 0.87 | 1.33 ± 0.24 | 1.21 ± 0.12 | 2.45 ± 0.29 | <.0001 |
| FT3 (pg/mL) # | 2.75 | 3.67 | 4.33 ± 0.45 | 4.26 ± 0.56 | 6.31 ± 1.41 | <.0001 |
| Physical Activity | 0.90 | |||||
| Sedentary (%) | 0 | 0 | 12 (4.9) | 0 | 0 | |
| Light (%) | 1 (100) | 1 (100) | 184 (75.7) | 5 (100) | 4 (80.0) | |
| Moderate/High (%) | 0 | 0 | 47 (19.4) | 0 | 1 (20.0) | |
| Smoking (current vs ever and never smoked) (n,%) | 0 | 0 | 85 (35.0) | 2 (40.0) | 1 (20.0) | 0.89 |
| Heart rate (beats/minute) # | 67.00 | 44.00 | 69.05 ± 11.01 | 71.80 ± 12.87 | 83.00 ± 22.27 | 0.005 |
| Body Mass Index (kg/m2) # | 26.48 | 27.29 | 26.12 ± 4.14 | 23.39 ± 5.21 | 25.58 ± 3.55 | 0.66 |
*
From Age- and Sex- Adjusted Linear or Logistic Regression Models as Appropriate.
#
Mean ± Standard Deviation
Reference normal values:
- TSH, 0.46 - 4.68 mIU/L
- FT3, 2.77 - 5.27 pg/mL
- FT4, 0.77 - 2.19 ng/dl