Table 2.
Characteristics of participants older than 65 years
| n=5 | n=25 | n=800 | n=71 | n=15 | ||
|---|---|---|---|---|---|---|
| Overt Hypothyroidism | Subclinical Hypothyroidism | Euthyroidism | Subclinical Hyperthyroidism | Overt Hyperthyroidism | P* | |
| Age (years) # | 76.20 ± 8.01 | 77.04 ± 7.42 | 75.34 ± 7.31 | 76.05 ± 8.27 | 78.54 ± 7.40 | 0.37 |
| Sex female (%) | 60.00 | 72.00 | 55.25 | 56.34 | 66.67 | 0.99 |
| Education (years) # | 6.00 ± 3.46 | 5.60 ± 4.32 | 6.71 ± 5.29 | 4.69 ± 2.18 | 4.27 ± 1.48 | 0.98 |
| Mini-Mental State Examination corrected score (0-30)# | 23.80 ± 5.12 | 24.84 ± 3.17 | 24.72 ± 4.52 | 22.61 ± 6.88 | 22.53 ± 5.94 | 0.002 |
| TSH (mUI/L) # | 52.00 ± 34.63 | 7.99 ± 4.74 | 1.54 ± 0.85 | 0.28 ± 0.13 | 0.04 ± 0.07 | <.0001 |
| FT4 (ng/dL) # | 0.51 ± 0.21 | 1.28 ± 0.31 | 1.45 ± 0.30 | 1.53 ± 0.30 | 2.48 ± 0.87 | <.0001 |
| FT3 (pg/mL) # | 2.91 ± 0.73 | 4.28 ± 0.58 | 4.23 ± 0.44 | 4.32 ± 0.44 | 6.19 ± 2.21 | <.0001 |
| Physical Activity | 0.13 | |||||
| Inactive/Light (%) | 3 (60.0) | 5 (20.0) | 168 (21.0) | 21 (29.6) | 7 (46.7) | |
| Moderate (%) | 2 (40.09 | 18 (72.0) | 590 (73.8) | 47 (66.2) | 7 (46.7) | |
| Intense (%) | 0 | 2 (8.0) | 42 (5.2) | 3 (4.2) | 1 (6.6) | |
| Smoking (current vs ever and never smoked) (n,%) | 1 (20.0) | 1 (4.0) | 118 (14.8) | 9 (12.7) | 3 (20.0) | 0.90 |
| Heart rate (beats/minute) # | 84.00 ± 23.58 | 70.42 ± 12.42 | 69.44 ± 12.04 | 72.13 ± 13.32 | 69.92 ± 11.01 | 0.99 |
| Body Mass Index (kg/m2) # | 33.24 ± 8.65 | 27.08 ± 4.79 | 27.27 ± 4.01 | 27.68 ± 4.09 | 26.91 ± 5.85 | 0.49 |
*
From Age- and Sex- Adjusted Linear or Logistic Regression Models as Appropriate.
#
Mean ± Standard Deviation
Reference normal values:
- TSH, 0.46 - 4.68 mIU/L
- FT3, 2.77 - 5.27 pg/mL
- FT4, 0.77 - 2.19 ng/dl