Table 2.

Single-SNP association results in the TGEN dataset.

order	SNP	interval of SNPs in the original paper	Minor Allele	F_A	F_U	OR	Allele.P	Geno.P	DOM.P	REC.P	TREND.P
T.1	rs4935774	1	1	0.215	0.201	1.09	0.39	0.54	0.54	0.29	0.38
T.2	rs676160	4~5	2	0.100	0.092	1.10	0.49	0.78	0.50	0.73	0.48
T.3	rs676759	5~6	2	0.389	0.378	1.05	0.57	0.35	0.88	0.19	0.57
T.4	rs560573	6	2	0.386	0.374	1.05	0.55	0.40	0.95	0.21	0.55
T.5	rs985421	6~7	2	0.016	0.022	0.74	0.28	NA	NA	NA	0.27
T.6	rs593769	6~7	1	0.385	0.374	1.05	0.57	0.48	0.98	0.25	0.57
T.7	rs12364988	7	2	0.496	0.477	1.08	0.33	0.56	0.61	0.28	0.34
T.8	rs668387	8	2	0.430	0.411	1.08	0.32	0.57	0.52	0.31	0.32
T.9	rs11218313	10~11	2	0.088	0.086	1.03	0.83	0.92	0.78	0.82	0.83
T.10	rs2276346	15	1	0.351	0.372	0.91	0.25	0.22	0.10	0.95	0.24
T.11	rs10502262	15~16	1	0.288	0.312	0.89	0.17	0.33	0.14	0.60	0.17
T.12	rs7131432	17~18	2	0.016	0.024	0.67	0.14	NA	NA	NA	0.14
T.13	rs10892756	18~19	1	0.075	0.068	1.11	0.49	0.40	0.65	0.18	0.49
T.14	rs11218346	18~19	1	0.085	0.078	1.11	0.48	0.60	0.55	0.37	0.47
T.15	rs1790213	18~19	2	0.375	0.393	0.93	0.33	0.34	0.17	0.99	0.33
T.16	rs11218347	18~19	1	0.076	0.073	1.04	0.78	0.94	0.81	0.78	0.78
T.17	rs1699103	20~21	1	0.404	0.442	0.85	0.045	0.13	0.07	0.14	0.043
T.18	rs7116734	20~21	1	0.399	0.419	0.92	0.30	0.42	0.61	0.19	0.29
T.19	rs11218350	20~21	2	0.215	0.248	0.83	0.040	0.11	0.11	0.07	0.045
T.20	rs10892759	22~23	1	0.325	0.368	0.83	0.021	0.040	0.011	0.35	0.020
T.21	rs1792113	22~23	1	0.351	0.375	0.90	0.20	0.06	0.041	0.68	0.21
T.22	rs11218360	22~23	1	0.027	0.032	0.83	0.42	NA	NA	NA	0.41
T.23	rs7128608	22~23	1	0.044	0.038	1.17	0.44	0.75	0.45	0.84	0.45
T.24	rs1629493	23~24	2	0.356	0.388	0.87	0.09	0.20	0.15	0.14	0.08
T.25	rs2282649	24	2	0.289	0.309	0.91	0.26	0.52	0.31	0.43	0.26
T.26	rs726601	24~25	2	0.296	0.329	0.86	0.07	0.12	0.038	0.56	0.06
T.27	rs1784931	24~25	1	0.377	0.415	0.86	0.049	0.12	0.049	0.24	0.046
T.28	rs1010159	25	1	0.336	0.363	0.89	0.14	0.32	0.21	0.24	0.14
T.29	rs1614735	27	2	0.479	0.505	0.90	0.19	0.27	0.11	0.58	0.18
T.30	rs17125558	27~28	2	0.020	0.022	0.90	0.70	NA	NA	NA	0.70
T.31	rs10892761	27~28	2	0.411	0.422	0.96	0.56	0.07	0.10	0.32	0.56

Notes: F_A: Minor allele frequency in cases; F_U: Minor allele frequency in controls; OR: estimated odds ratio for AD of minor allele; Allele.P: p-value for allelic association; Geno.P: p-value for genotypic (2 df) test; DOM.P: p-value for genotypic (1 df) test with dominant model; REC.P: p-value for genotypic (1 df) test with recessive model; TREND.P: Cochran-Armitage trend test; NA: Not available (allelic, genotypic and dominant/recessive tests require that each cell has a frequency of 1 or greater). SNPs studied by both Rogaeva et al. [1] and Reiman et al. [4] are indicated in boldface.