Fig. 2.
Composition of skin window exudates and the effects of immune modulators. a. Differential leukocyte influx over the 48 h following traumatisation. Results are expressed as mean ± SEM, n = 3 for each time point. b, c. Concentration of inflammatory mediators assayed at 30 min (b) and 24 h (c) after creation of lesions. Mean values are shown. d. Representative western blot of cellular exudates showing that application of MDP (M) increases myeloperoxidase (MPO) and lactoferrin (LF) content relative to saline-treated (S) windows. Albumin (Alb) extravasation into exudate fluid was unchanged. e, f. Exogenous IL-8 augments neutrophil recruitment (e) and IL-1β (f) production. Results are expressed as mean ± SEM, n = 3.
