Skip to main content
. Author manuscript; available in PMC: 2009 Sep 11.
Published in final edited form as: J Med Chem. 2008 Aug 15;51(17):5264–5270. doi: 10.1021/jm800045t

Figure 1.

Figure 1

Chemical structures of 1 and 2, the two α-ketoamide calpain inhibitors used in this study. Both compounds contain a P1 α-aminobutanoic acid and P2 leucine residue, but the primed side extension of 1 ends with adenine ring, while that of 2 is terminated by a piperazine ring. The structure of the commercially available calpain inhibitor AK-295 is also shown for comparison.