. 2008 Dec 1;77(2):642–656. doi: 10.1128/IAI.01141-08

TABLE 3.

Eucaryotic-like ORFs of C. burnetii isolates

ORF designation	ORF alias(es) in isolate:				Recognized motif^a	Best e-value	G+C content (%)
ORF designation	NM	K	G	Dugway	Recognized motif^a	Best e-value	G+C content (%)
None	Cbu1158	CbuK1025	CbuG0851^b	CbuD1256	Sterol reductase (sterol delta-7-reductase)	8.4E-32	40.07
None	Cbu1206	CbuK1070	CbuG0804	CbuD1293	Sterol reductase [-sterol reductase]	4.1E-156	39.72
HmgA	Cbu0610	CbuK1440	CbuG1393	CbuD0622	Hydroxymethylglutaryl-coenzyme A reductase	4.0E-59	49.39
None	Cbu0609	CbuK1441	CbuG1394	CbuD0621	Mevalonate kinase	5.0E-14	43.14
MvaK	Cbu0608	CbuK1442	CbuG1395	CbuD0620	Phosphomevalonate kinase	8.0E-16	44.83
MvaD	Cbu0607	CbuK1443	CbuK1396	CbuD0619	Diphosphomevalonate decarboxylase	3.0E-36	43.21
None	Cbu0175	CbuK0362	CbuG1837	CbuD1925	Protein kinase (STPK)	2.3E-04	39.7
None	Cbu1168-Cbu1168a^b	CbuK1031^b	CbuG0843^b	CbuD1261	Protein kinase (STPK)	1.7E-10	36.95
None	Cbu1377-Cbu1379^b	CbuK1237	CbuG0633^c	CbuD1462e-CbuD1462f^b	Protein kinase	2.9E-09	37
AnkP	Cbu0069-Cbu0070-Cbu0071^b	CbuK1981a		CbuD2035	Ankyrin repeats	3.3E-02	43.68
AnkA	Cbu0072	CbuK1982		CbuD2034^d	Ankyrin repeats	2.8E-02	44.87
AnkB	Cbu0144-Cbu0145^b	CbuK1907^c	CbuG1870^b	CbuD1961-CbuD1960^b	Ankyrin repeats	2.1E-07	45
AnkC	Cbu0201	CbuK0392	CbuG1805	CbuD1894	Ankyrin repeats	2.9E-07	48.09
AnkD	Cbu0355-Cbu0356^b	CbuK0551^b	CbuG1652^c	CbuD1724	Ankyrin repeats and F box	6.2E-03 and 5.7E-04	41.47
AnkF	Cbu0477	CbuK1384	CbuG1537	CbuD1598	Ankyrin repeats	3.3E-04	44.75
AnkG	Cbu0781	CbuK0651^c	CbuG1220	CbuD0829	Ankyrin repeats	4.2E-04	39.35
AnkH	Cbu1024-Cbu1025^b	CbuK0815^b	CbuG0983^b	CbuD1019	Ankyrin repeats	2.0E-05	38.54
AnkI	Cbu1213^c		CbuG0798	CbuD1298	Ankyrin repeats	1.4E-03	39.2
AnkJ	Cbu1253-Cbu1254^b	CbuK1113^b	CbuG0758^b	CbuD1337-CbuD1338^b	Ankyrin repeats	1.6E-06	38
AnkK	Cbu1292	CbuK1155	CbuG0716	CbuD1380	Ankyrin repeats	6.1E-10	40.57
AnkL	Cbu1608-Cbu1609-Cbu1610-Cbu1611^b	CbuK1835^b	CbuG0406^c	CbuD0382^c	Ankyrin repeats	1.8E-11	36
AnkM	Cbu1757-Cbu1758^b	CbuK0249^b	CbuG0139^c	CbuD0245	Ankyrin repeats	1.9E-06	40.66
AnkN		CbuK1330	CbuG1487	CbuD1552-CbuD1553^b	Ankyrin repeats	1.4E-05	42.89
AnkO				CbuD1108	Ankyrin repeats	6.3E-08	39.32
None	Cbu0814-Cbu0815-Cbu0816^b	CbuK0684	CbuG1185^b	CbuD0881-CbuD0882^b	F box and RCC domain	8.4E-02 and 8.0E-17	42.09
None	CbuA0014				F box	2.5E-03	35.93
None	Cbu1217	CbuK1077^c	CbuG0795^b	CbuD1300-CbuD1301^b	Hect-like E3 ubiquitin ligase and RCC domain	4.0E-11 and 8.0E-21	37.61
None				CbuD1106-CbuD1107^b	F box	1.60E-01	33.93
None	Cbu0820-Cbu0821^b	CbuK0688	CbuG1181^b	CbuD0886	LRR	6.0E-04	38.37
None	Cbu0295	CbuK0492^b	CbuG1710^b	CbuD1787	SEL1 TPR	7.9E-03	38.79
None	Cbu0530	CbuK1306	CbuG1464	CbuD1533	TPR	1.1E-03	43.87
None	Cbu0547	CbuK1291	CbuG1449	CbuD1516	TPR	4.2E-11	39.99
EnhC	Cbu1136	CbuK1003	CbuG0874	CbuD1234^d	SEL1 TPR (enhanced entry protein EnhC)	4.4E-11	37.77
None	Cbu1160	CbuK1026^d	CbuG0849	CbuD1257^d	TPR	5.0E-08	35.52
None	Cbu1364-Cbu1365^b	CbuK1225^c	CbuG0647^b	CbuD1452	TPR	2.4E-07	40.1
None	Cbu1457	CbuK1685^c	CbuG0554	CbuD0496^c	SEL1 TPR	2.30E-09	40.58
None				CbuD0785	TPR	1.00E-01	39.6
None				CbuD0795	TPR	2.1E-03	43.84
None				CbuDA0024	SEL1 TPR	2.9E-03	44.25
None	Cbu0870	CbuK0737	CbuG1132	CbuD0934	TPR-like	7.1E-23	35.37
None	Cbu0488	CbuK1372	CbuG1525	CbuD1588	Metallophosphatase [bis(5′-nucleosyl)-tetraphosphatase]	1.8E-12	43.83
LpxH	Cbu1489	CbuK1720	CbuG0517	CbuD0532	Metallophosphatase (UDP-2,3-diacylglucosamine hydrolase)	4.5E-12	43.07
ApaH	Cbu1987	CbuK2037	CbuG1994	CbuD2085	Metallophosphatase [bis(5′-nucleosyl)-tetraphosphatase]	9.0E-11	46.05
None	CbuA0032	CbuKA0035		CbuDA0061	Metallophosphatase (3′,5′-cyclic-nucleotide phosphodiesterase)	4.7E-22	32.29
None	Cbu0189-Cbu0190^b	CbuK0381	CbuG1816^b	CbuD1905-CbuD1906^b	Cyclic nucleotide monophosphate binding metallophosphatase and CAAX amino-terminal protease	7.1E-26 and 1.0E-04	35.57
None	Cbu0593-Cbu0594-Cbu0595^b	CbuK1245^b	CbuG1406^c	CbuD1472	Cyclic nucleotide monophosphate binding metallophosphatase and CAAX amino-terminal protease	1.6E-03 and 9.5E-04	38.76
None	Cbu1482	CbuK1713	CbuG0524	CbuD0526	SPHF/band 7 domain (stomatin/prohibitin homologs)	2.5E-52	44.44
Cls	Cbu0096	CbuK1960	CbuG1921	CbuD2014	Cardiolipin synthetase	8.5E-06	43.73
None	Cbu0886a-Cbu0886b^b	CbuK0752	CbuG1115^b	CbuD0952^c	Patatin-like phospholipase	1.9E-23	42.4
None	Cbu0916a-Cbu0916b^b	CbuK0919	CbuG1087^c	CbuD1157^c	Cyclic nucleotide monophosphate binding metallophosphatase and patatin-like phospholipase	4.4E-23 and 3.1E-44	35.93
None				CbuDA0012	Phospholipase D	1.4E-06	42.38
None	Cbu0898	CbuK0763	CbuG1104	CbuD0962	Thyroglobulin type-1 repeat (thyroid-related protein)	5.0E-14	38.48
None	Cbu0335^c	CbuK0531	CbuG1671	CbuD1744	Acid phosphatase	9.9E-43	40.23
None	Cbu1730	CbuK0277	CbuG0111	CbuD0272	Phosphoserine phosphatase	2.0E-14	43
DedA	Cbu0519	CbuK1318	CbuG1476	CbuD1543	SNARE-associated golgi protein	9.6E-05	41.25

Coiled-coil domains were not included in this analysis.

Frameshifted ORFs comprising a pseudogene.

Shorter ORF relative to isolate orthologous ORFs.

Longer ORF relative to isolate orthologous ORFs.