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. 2008 Nov 21;191(3):1018–1025. doi: 10.1128/JB.01340-08

TABLE 3.

Distribution of LSPs across M. aviuma

Species Strain Southern blot Non map specific
M. avium subsp. paratuberculosis specific
M. avium subsp. paratuberculosis lineage specific
LSPP 1 LSPP 3 LSPP 5 LSPP 6 LSPP 7e LSPP 8f LSPP 10 LSPP 13 LSPP 17 LSPP 2b LSPP 4 LSPP 11 LSPP 12 LSPP 14 LSPP 15 LSPP 16c LSPA 8 GPLd LSPA 4-II MAV 14 LSPA 18 LSPA 20 Deletion 2 VA 15 LSPA 11
M. avium subsp.
    hominissuis 104 Yes - i i + 104 + + + + + + +
MB063764 Yes + + + i + + + + + + + + +
ATCC 49601 Yes + i + + + + i i + 104 + + + + + + +
76102 Yes + i + + + i + i + 104 + + + + + + +
108 No + i + + + i + i + 104 + + + + + + +
DV Yes + i + i + 104 + + + + + + +
28132 Yes + i + i + 104 + + + + + + +
MB064490 Yes + i + i + 104 + + + + + + +
2000-325 No + + + + + i ND i + + + ND + + + + +
HMC36A No + + + + i + + + + + + + + +
    avium ATCC 25291T Yes + + + + i i i + + + i + + + + +
ATCC 35713 Yes + + + + i i i + + + i + + + + +
ATCC 15796 Yes + + + + i i i + + + i + + + i +
    silvaticum ATCC 49884T Yes + + + + i i i + + + i + + + i +
9800851 No + + + + i i i + + + i + + + i +
    paratuberculosis, cattle genotype MAP K-10 Yes + + + + + + + + + + + + + + + + K-10 + + + +
316F Yes + + + + + + + + + + + + + + + + K-10 + + + +
MAP 119 Yes + + + + + + + + + + + + + + + + K-10 + + + +
7296 Yes + + + + + + + + + + + + + + + + K-10 + + + +
    paratuberculosis, sheep genotype 6756 Yes + + + + + + + + + + + + + + + + + + + + + +
85/14 Yes + + + + + + + + + + + + + +/- + + + + + + i +
LN20 Yes + + + + + + + + + + + + + + + + + + + + +
P465 Yes + + + + + + + + + + + + + + + + + + + + + +
M. intracellulareg ATCC 13950T No + + MIh MI + + + + + + + +
a

+, Positive by multiplex PCR, LSP present; −, negative by multiplex PCR, LSP absent; i, internal target not detected, LSP absent; +/−, see the text (strain-specific deletion after acquisition of LSPP14). For the non-M. avium subsp. paratuberculosis-specific LSPs, the location previously described was absent in strain 104 (17). For the M. avium subsp. paratuberculosis-specific and M. avium subsp. paratuberculosis-lineage-specific LSPs, the locations can be found in Table S2 in the supplemental material. ND, not determined.

b

In negative strains, LSPP2 is replaced by the LSPA21 polymorphism.

c

In negative strains, LSPP16 is replaced by the LSPA24 polymorphism.

d

In negative strains, GPL conformation can match that found in M. avium subsp. paratuberculosis strain K-10 or M. avium subsp. hominissuis strain 104.

e

In negative strains, LSPP7 is replaced by the MAV15 polymorphism.

f

In negative strains, LSPP8 is replaced by the LSPA15 polymorphism, except for strain HMC36A, which exhibits a unique polymorphism.

g

In negative strains, some LSPs are replaced by M. intracellulare-specific polymorphisms.

h

MI, M. intracellulare.