TABLE 3.
Normalized levels of nrd gene transcripts in mycobacteria during early-logarithmic-phase aerobic growth in Middlebrook 7H9 medium
| Organism | Expression level of the transcript of the following gene relative to that of sigAa:
|
||||
|---|---|---|---|---|---|
| nrdE | nrdF2 | nrdF1 | nrdB | nrdZ | |
| M. tuberculosis H37Rv | 5.2 ± 0.9 | 5.1 ± 0.2 | 1.4 ± 0.1 | 0.91 ± 0.34 | 0.13 ± 0.06 |
| M. smegmatis mc2155 | 60 ± 3 | 17 ± 4 | N/A | 5.5 ± 1.8 | N/A |
| M. smegmatis ΔDRKIN | 38 ± 7 | 9.6 ± 3.6 | N/A | 4.9 ± 1.0 | N/A |
a
Expression levels were measured in cultures at an OD600 of 0.3. N/A, not applicable.