TABLE 1.
MICs of grape extracts and compounds on H. pylori growth by agar dilution assay
| Extract/compounda | MIC (μg/ml) of H. pylori strainb:
|
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| G2-1 | 26695 | WV99 | NB2-1 | 1324P-1 | D5251 | D5131 | D5178 | D5136 | D5135 | SS1 | P1pDH80 | |
| RGS | 1,024 | 512 | 512 | 512 | 512 | 1,024 | 512 | 512 | 512 | 512 | − | − |
| WGS | 1,024 | 512 | 1,024 | 512 | 512 | 1,024 | 512 | 512 | 512 | 512 | − | − |
| BGS | 1,024 | 512 | 1,024 | 1,024 | 512 | 2,048 | 512 | 512 | 512 | 512 | − | − |
| MSN | 256 | 256 | 256 | 512 | 256 | 256 | 512 | 512 | 256 | 512 | 512 | 512 |
| MSD | 512 | 1,024 | 512 | 256 | 256 | 256 | 1,024 | 1,024 | 512 | 1,024 | 512 | 1,024 |
| MSY | 512 | 512 | 1,024 | 512 | 1,024 | 512 | 512 | 1,024 | 512 | 1,024 | 512 | 512 |
| RSV | − | 12.5 | − | − | − | − | − | − | − | − | 6.25 | 12.5 |
| ELA | − | 50 | − | − | − | − | − | − | − | − | 12.5 | 12.5 |
| MYR | − | >50 | − | − | − | − | − | − | − | − | >50 | >50 |
a
RGS, red grape skin; WGS, white grape skin; BGS, black grape skin; MSN, muscadine grape skin; MSD, muscadine grape seed; MSY, muscadine grape synergy; RSV, resveratrol; ELA, ellagic acid; MYR, myricetin.
b
Average MIC at 72 h by agar dilution assay. Each experiment was performed in duplicate. −, not determined.