Skip to main content
. 2005 Sep 15;32(1):179–194. doi: 10.1093/schbul/sbi048

Table 2.

Study Design Characteristics and Associated Mean (+ SD) Effect Sizes

Design characteristic n of Studies (%) n of Effect Sizes Mean Effect Size (SD)
Diagnostic System for Probands
 Research Diagnostic Criteria 7 (12) 37 0.28 (0.35)
Diagnostic and Statistical Manual of Mental Disorders, 3rd ed. 2 (3) 8 0.37 (0.43)
Diagnostic and Statistical Manual of Mental Disorders, 3rd ed.—revised 31 (54) 157 0.38 (0.35)
International Classification of Diseases, 9th revision 1 (2) 1 −0.08 (−)
Diagnostic and Statistical Manual of Mental Disorders, 4th ed. 14 (24) 74 0.45 (0.37)
 Operational Criteria for Psychotic Illness 3 (5) 8 0.34 (0.26)
Type of First-Degree Relatives
 Siblings 17 (29) 63 0.41 (0.38)
 Parents 6 (10) 27 0.45 (0.31)
 Offspring 3 (5) 9 0.36 (0.26)
 Monozygotic twins 1 (2) 18 0.42 (0.30)
 Parents and siblings 11 (19) 69 0.39 (0.35)
 Siblings and offspring 1 (2) 20 0.35 (0.23)
 Parents, siblings, and offspring 10 (17) 53 0.25 (0.35)
 Not reported 9 (16) 26 0.53 (0.47)
Groups Matched on Age
 Yes 45 (78) 224 0.36 (0.35)
 No 11 (19) 55 0.48 (0.40)
 Not reported 2 (3) 6 0.27 (0.28)
Groups Matched on Education
 Yes 36 (62) 167 0.34 (0.36)
 No 9 (16) 66 0.45 (0.29)
 Not reported 13 (22) 52 0.45 (0.41)
Presence of Schizotypal Symptomsa
 Yes 21 (36) 102 0.39 (0.30)
 No 20 (35) 120 0.35 (0.36)
 Not reported 17 (29) 63 0.43 (0.42)
Asymmetric Inclusion Criteria
 Yes 21 (36) 115 0.44 (0.40)
 No 30 (52) 134 0.34 (0.32)
 Not reported 7 (12) 36 0.36 (0.32)
a

“Yes” indicates that schizotypy was assessed and elevated rates of symptoms/schizotypal personality diagnoses were reported in the relative group; “no” indicates that schizotypy was assessed and either screened out of the relative group or reported as not significantly elevated compared to controls; “not reported” indicates that no assessment of schizotypy was described.