Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Predominant Polarity Correlates
| Depressive Polarity | Manic Polarity |
| 60% bipolar patients | 40% bipolar patients |
| More bipolar II | More bipolar I |
| More depressive onset | More manic onset |
| More seasonal pattern | Younger and earlier onset |
| More suicide attempts | More substance misuse |
| Better long-term response to lamotrigine | Better long-term response to atypical antipsychotics |
| More antidepressant use |
