Table 2.
Marker-to-Marker LD in the RGS4 locus
| SNPa | M1 | M2 | M3 | M4 | M5 | M6 | M7 | M8 | M9 | M10 | M11 | M12 | M13 | M14 | M15 | M16 | M17 | M18 | M19 | M20 | M21 | M22 | M23 | M24 |
| M1 | 0.01 | 0.55 | 0.55 | 1.00 | 0.04 | 0.03 | 0.04 | 0.03 | 0.04 | 0.04 | 0.04 | 0.00 | 0.91 | 0.02 | 0.04 | 0.04 | 0.91 | 0.04 | 0.04 | 0.77 | 0.04 | 0.05 | 0.02 | |
| M2 | 0.95 | 0.03 | 0.03 | 0.02 | 0.21 | 0.14 | 0.15 | 0.14 | 0.15 | 0.15 | 0.23 | 0.04 | 0.01 | 0.65 | 0.23 | 0.21 | 0.01 | 0.21 | 0.12 | 0.00 | 0.11 | 0.01 | 0.01 | |
| M3 | 1.00 | 1.00 | 1.00 | 0.55 | 0.07 | 0.04 | 0.05 | 0.04 | 0.05 | 0.05 | 0.06 | 0.01 | 0.51 | 0.03 | 0.07 | 0.06 | 0.53 | 0.06 | 0.05 | 0.41 | 0.05 | 0.08 | 0.00 | |
| M4 | 1.00 | 1.00 | 1.00 | 0.55 | 0.07 | 0.04 | 0.05 | 0.04 | 0.05 | 0.05 | 0.06 | 0.01 | 0.51 | 0.03 | 0.07 | 0.06 | 0.53 | 0.06 | 0.05 | 0.41 | 0.05 | 0.08 | 0.00 | |
| M5 | 1.00 | 0.98 | 1.00 | 1.00 | 0.04 | 0.03 | 0.04 | 0.03 | 0.04 | 0.04 | 0.04 | 0.00 | 0.91 | 0.02 | 0.04 | 0.04 | 0.91 | 0.04 | 0.04 | 0.77 | 0.04 | 0.05 | 0.02 | |
| M6 | 1.00 | 0.70 | 1.00 | 1.00 | 1.00 | 0.71 | 0.71 | 0.67 | 0.71 | 0.71 | 0.96 | 0.10 | 0.03 | 0.43 | 0.96 | 0.92 | 0.04 | 0.95 | 0.61 | 0.01 | 0.60 | 0.43 | 0.00 | |
| M7 | 1.00 | 0.66 | 0.83 | 0.83 | 1.00 | 0.98 | 0.99 | 1.00 | 0.99 | 0.99 | 0.71 | 0.13 | 0.03 | 0.32 | 0.73 | 0.69 | 0.03 | 0.71 | 0.89 | 0.03 | 0.91 | 0.60 | 0.00 | |
| M8 | 1.00 | 0.68 | 0.83 | 0.83 | 1.00 | 0.98 | 1.00 | 0.95 | 1.00 | 1.00 | 0.71 | 0.13 | 0.03 | 0.32 | 0.73 | 0.68 | 0.03 | 0.71 | 0.86 | 0.02 | 0.90 | 0.60 | 0.00 | |
| M9 | 1.00 | 0.66 | 0.84 | 0.84 | 1.00 | 0.98 | 1.00 | 1.00 | 0.95 | 0.95 | 0.70 | 0.14 | 0.03 | 0.32 | 0.72 | 0.66 | 0.03 | 0.71 | 0.88 | 0.04 | 0.91 | 0.60 | 0.00 | |
| M10 | 1.00 | 0.68 | 0.83 | 0.83 | 1.00 | 0.98 | 1.00 | 1.00 | 1.00 | 1.00 | 0.71 | 0.13 | 0.03 | 0.32 | 0.73 | 0.68 | 0.03 | 0.71 | 0.86 | 0.02 | 0.90 | 0.60 | 0.00 | |
| M11 | 1.00 | 0.68 | 0.83 | 0.83 | 1.00 | 0.98 | 1.00 | 1.00 | 1.00 | 1.00 | 0.71 | 0.13 | 0.03 | 0.32 | 0.73 | 0.68 | 0.03 | 0.71 | 0.86 | 0.02 | 0.90 | 0.60 | 0.00 | |
| M12 | 1.00 | 0.71 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 0.09 | 0.03 | 0.46 | 0.97 | 0.93 | 0.03 | 0.95 | 0.63 | 0.03 | 0.60 | 0.40 | 0.00 | |
| M13 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 0.00 | 0.04 | 0.10 | 0.09 | 0.00 | 0.09 | 0.12 | 0.00 | 0.13 | 0.08 | 0.00 | |
| M14 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 0.01 | 0.03 | 0.03 | 1.00 | 0.03 | 0.03 | 1.00 | 0.03 | 0.04 | 0.02 | |
| M15 | 1.00 | 0.80 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 0.44 | 0.43 | 0.02 | 0.42 | 0.26 | 0.01 | 0.24 | 0.06 | 0.03 | |
| M16 | 1.00 | 0.71 | 1.00 | 1.00 | 1.00 | 0.99 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 0.94 | 0.03 | 0.95 | 0.65 | 0.03 | 0.62 | 0.40 | 0.00 | |
| M17 | 1.00 | 0.66 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 0.99 | 1.00 | 1.00 | 0.95 | 1.00 | 0.03 | 0.99 | 0.67 | 0.04 | 0.65 | 0.43 | 0.00 | |
| M18 | 1.00 | 0.71 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 0.03 | 0.04 | 1.00 | 0.03 | 0.04 | 0.02 | |
| M19 | 1.00 | 0.68 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 0.99 | 1.00 | 1.00 | 0.95 | 1.00 | 1.00 | 1.00 | 0.70 | 0.03 | 0.67 | 0.42 | 0.00 | |
| M20 | 1.00 | 0.58 | 0.84 | 0.84 | 1.00 | 0.86 | 1.00 | 0.99 | 1.00 | 0.99 | 0.99 | 0.89 | 1.00 | 1.00 | 0.84 | 0.89 | 0.93 | 1.00 | 0.94 | 0.03 | 0.96 | 0.59 | 0.00 | |
| M21 | 0.91 | 0.08 | 0.83 | 0.83 | 0.91 | 0.54 | 1.00 | 0.77 | 1.00 | 0.77 | 0.77 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 0.03 | 0.04 | 0.02 | |
| M22 | 1.00 | 0.56 | 0.85 | 0.85 | 1.00 | 0.87 | 1.00 | 0.99 | 1.00 | 0.99 | 0.99 | 0.88 | 1.00 | 1.00 | 0.83 | 0.89 | 0.93 | 1.00 | 0.93 | 1.00 | 1.00 | 0.63 | 0.00 | |
| M23 | 1.00 | 0.12 | 1.00 | 1.00 | 1.00 | 0.66 | 0.90 | 0.90 | 0.90 | 0.90 | 0.90 | 0.64 | 0.90 | 1.00 | 0.38 | 0.63 | 0.68 | 1.00 | 0.67 | 0.83 | 1.00 | 0.87 | 0.02 | |
| M24 | 1.00 | 0.11 | 0.36 | 0.36 | 1.00 | 0.01 | 0.02 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.04 | 1.00 | 0.20 | 0.04 | 0.05 | 1.00 | 0.04 | 0.09 | 1.00 | 0.09 | 0.19 |
Note: SNP, single-nucleotide polymorphism; LD, linkage disequilibrium; SNP numbers M6, M9, M12, and M20 are SNP1, SNP4, SNP7, and SNP18, respectively, as previously reported13; number of Caucasian samples used in the LD analysis = 308 parents of schizophrenia probands; correlation coefficient r2 above diagonal, Lewontin D′ below.
a
Numbers are same as indicated in table 1.