Table 3.
Results and Conclusions
| Study | Results | Author's Conclusions |
| Soteria USA (2 cohorts): Mosher et al13; Mosher14; Mosher and Menn15; Mosher and Menn16; Mosher and Menn17; Mosher and Menn18; Mathews et al19; Mosher 20; Mosher et al21; Mosher22; Bola23 Bola and Mosher24; Bola and Mosher.25 | Marginal effects of experimental treatment on 2-y outcomes (30 comparisons) | “Soteria treatment resulted in better two-year outcomes for patients with newly diagnosed schizophrenia spectrum psychoses …” |
| Endpoint N = 160 | ||
| Completers N = 129 | ||
| Completers adjusted for attrition bias N = 129 | ||
| Composite outcome | ||
| Endpoint NS | ||
| Completers NS | ||
| Completers adjusted for attrition bias <0.05 | ||
| Social functioning | ||
| Endpoint NS | ||
| Completers NS | ||
| Completers adjusted for attrition bias NS | ||
| Global psychopathology | ||
| Endpoint NS | ||
| Completers <0.05 | ||
| Completers adjusted for attrition bias <0.05 | ||
| Improved psychopathology | ||
| Endpoint NS | ||
| Completers NS | ||
| Completers adjusted for attrition bias NS | ||
| Working any | ||
| Endpoint NS | ||
| Completers NS | ||
| Completers adjusted for attrition bias NS | ||
| Working full time | ||
| Endpoint NS | ||
| Completers NS | ||
| Completers adjusted for attrition bias NS | ||
| Living alone or with peers | ||
| Endpoint <0.05 | ||
| Completers NS | ||
| Completers adjusted for attrition bias NS | ||
| Readmission | ||
| Endpoint NS | ||
| Completers NS | ||
| Completers adjusted for attrition bias <0.05 | ||
| Number of readmissions | ||
| Endpoint NS | ||
| Completers NS | ||
| Completers adjusted for attrition bias NS | ||
| Days in readmission | ||
| Endpoint NS | ||
| Completers NS | ||
| Completers adjusted for attrition bias NS | ||
| Soteria Bern: Ciompi et al10; Ciompi26; Ciompi and Bernascomi27; Ciompi et al28; Ciompi et al29; | Only 2 outcomes showed significant differences between the 2 groups: mean daily dose of medication (P < .01) and total dose of medication (P < .05)—(9 comparisons) | “The two-year outcome revealed no significant differences between Soteria patients and controls ….” |
Note: NS, not significant.