Table 1.
Effect Sizes (Cohen d) of Relatives Vs Controls and Relatives Vs Patients Group Differences, Where Calculated and Not Limited by Statistical Heterogeneity in the Meta-analyses of Boos et al,34 With Comparable Results for First-Episode Patients Vs Controls From the Meta-analysis by Vita et al13
| Region | Effect Size (95% CI) for Relatives Vs Controls | Effect Size (95% CI) for Patients Vs Relatives | Effect Size (95% CI) for First-Episode Patients Vs Controls |
| Hippocampus | −0.47 (−0.34 to −0.61) | −0.29 (not given) | −0.66 (−0.45 to −0.87) [left side] |
| Gray matter | −0.18 (−0.02 to −0.33) | Not examined | Not examined |
| Third ventricle | −0.21 (−0.03 to −0.40) | Not examined | −0.59 (−0.38 to −0.80) |