Table 1.

Mean Values and SDs (M ± SD) of 17β-Estradiol and Other Hormones in Women With Schizophrenia (n = 19) During the Periovulatory Phase of the Menstrual Cycle Under Active Drug (Estrogen Replacement) and Placebo Conditions; Normal Reference Values for the Periovulatory Phase According to Klinga⁷²; Differences Between Active Drug and Placebo Conditions and the Effect of Time Were Calculated by Means of Random-Effect Regression Analysis

Hormone	Normal Reference Values	Active Drug	Placebo	P
17β-Estradiol (pg/mL)	150–350	192 ± 91	56 ± 57	<.001
LH (mU/mL)	30–80	4.3 ± 6.4	10.6 ± 11.4	.011
FSH (mU/mL)	2–14	6.8 ± 10.7	16.1 ± 22.8	.044
Prolactin (mU/mL)	70–410	1169 ± 1060	891 ± 933	.009
Testosterone (pg/mL)	200–600	399 ± 155	469 ± 247	.466
DHEA-S (ng/mL)	350–4300	2439 ± 967	2448 ± 997	.717

Note: LH, luteinizing hormone; FSH, follicle-stimulating hormone; DHEA-S, dehydroepiandrosterone sulfate.

The P values in the table are the results of Wald tests of the drug effect.