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. Author manuscript; available in PMC: 2009 Jan 28.
Published in final edited form as: J Neurovirol. 2007 Oct;13(5):433–445. doi: 10.1080/13550280701460565

Figure 6.

Figure 6

Intrnasal infection of mice with wt VSV induces type I IFN expression in mouse lungs and results in replication of VSV in mouse brains, spleens and lungs. Mice were infected i.n. with wt VSV (1 × 104 PFU) or mock-infected and sacrificed 24 h p.i. RT-PCR was used to detect IFN-α and IFN-β mRNA expression in the lungs of 3 infected and 1 mock-infected mice (A). GAPDH was used as housekeeping gene control. Homogenates from mouse brains, spleens and lungs taken at day 1 p.i. were subjected to plaque assays to detect the presence of VSV in these tissues (B; n = 3 per group).