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. Author manuscript; available in PMC: 2010 Jan 1.
Published in final edited form as: Peptides. 2008 May 28;30(1):111–122. doi: 10.1016/j.peptides.2008.05.016

Figure 3.

Figure 3

Confocal microscopy of the rat median eminence. The images were captured at a single focal plane of approximately 0.80 μm in thickness. A: Color-combined image of GnRH (green) and proNKB (red)- immunofluorescence showing dense intermingling and multiple foci of close apposition (arrowheads). B: In contrast, combined images of GnRH (green) and NK3R (red)-immunofluorescence show punctate colocalization of NK3R on GnRH fibers (yellow, arrows). The asterisks in A and B mark the edge of the lateral palisade zone. These studies provide morphological evidence that NKB modulates GnRH secretion at the level of the rat median eminence. Scale bar = 5μm in A (applies to A, B). From Krajewski et al., [56] reproduced with permission Wiley-Liss Inc.