Table I.
Incidence of PES-induced non-sustained AF in “healthy” atrial preparations in the presence of low concentration of 4-AP.
Control | 4-AP 10 µM | 4-AP 25 µM | 4-AP 50 µM |
---|---|---|---|
0/12 (0%)* | 1/12 (8%) | 3/12 (25%) | 4/12 (33%) |
PES induced non-sustained arrhythmias (≤ 1 sec) in 2 out of 14 atrial preparations under control conditions. These two preparations were excluded from further study.