Table 2.
Real-time quantitative RT-PCR analysis of changes in expression of genes encoding tight junction proteins in response to down-regulation of CD24
| Gene | Ratio of average gene of interest (GOI): Test (silenced CD24)/Control (plasmid only) |
Paired t-test P value (two tailed) |
| ZO-1 | -5 | < 0.05 |
| ZO-2 | -2.27 | < 0.01 |
| occludin | -6.25 | < 0.05 |
| claudin-3 | Not detected | |
| claudin-7 | -1.3 | < 0.05 |
| par-3 | -11.76 | < 0.05 |
| par-6 | Not detected |