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Culture of peripheral blood mononuclear cells (PBMC) in the presence of type I interferon (IFN) increases the number of CD56bright NK cells. The PBMC from healthy donors (n = 4) were cultured for 3 days in the presence of the indicated cytokines. The number of CD56bright NK cells per ml of cell culture was analysed and compared to the number found in the medium control. The fold increase in CD56bright NK cell is plotted. Paired t-test: P = 0·01 unstimulated compared to IFN-stimulated.
