Fig. 1.
Ascaris suum muscle bag preparation for recording current-clamp and voltage-clamp experiments. (A) Diagram of the location of two micropipettes for making current-clamp and voltage-clamp recordings from bag region of A. suum somatic muscle. The current-injecting pipette and the voltage-sensing pipette are shown. (B) Current-clamp recording showing 40 nA, 0.5 s, current pulses (upper trace) inducing change in membrane potential (lower trace). (C) Voltage-clamp recording showing depolarising step-voltage from a holding potential of −35 mV to 0 mV (upper trace) producing a current response (leak subtracted lower trace). Note the presence of the voltage-activated transient inward current (Ipeak) and a sustained inward current (Iss).